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Network activity and translational regulation in SHANK2 ASD neurons
2019 Predoctoral Fellowships
Hospital for Sick Children
Toronto, Ontario
Canada
Toronto, Ontario
Canada
This study will use induced pluripotent stem cells to investigate overconnection of neurons that carry a variation of the SHANK2 gene. By looking at these neural pathways, researchers may identify new targets for intervention that affect SHANK2 function.
- Keywords:
- Physiology/ Biology
- Cell Culture
- Cellular Biology
- Electrophysiology - Cellular
- In-Vitro Models
- Molecular Biology
- Gene Knock-Out/ Knock-In Models
- Biology
- Screening/ Diagnosis/ Phenotyping
- Cultured Neurons
- Undifferentiated Cells
- Cell Lines
- Stem Cells
| Type | Date | Title/Link |
|---|---|---|
| Publication | 02/16/2022 | Multielectrode Arrays for Functional Phenotyping of Neurons from Induced Pluripotent Stem Cell Models of Neurodevelopmental Disorders |
Status:
CompletedInvestigator:
McCready, FraserMentor:
Ellis, JamesGrant Term:
2 yearsAward Type:
Predoctoral FellowshipsGrant Amount:
$70,000.00Institution Website:
http://www.sickkids.caGrant ID:
11879