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Microglial-derived neuroactive cytokines governing neural circuit excitatory-inhibitory balance
2019 Predoctoral Fellowships
UMass Chan Medical School
Worcester, Massachusetts
United States
Worcester, Massachusetts
United States
This study will investigate the inflammatory microglia in mice as a contributor to the excitatory-inhibitory balance of neurons. The mouse data will also be compared with functional MRI data of human subjects who have ASD and inflammatory markers to identify new targets for treating ASD.
- Keywords:
- Neuroscience
- Immune Factors
- Neurobiology
- Structural Neuroimaging
- MRS
- Biology
- Etiology/ Risk Factors
- Adolescents/ Young Adults (13-25 Years)
- Autism Spectrum Disorder
- Mice
| Type | Date | Title/Link |
|---|---|---|
| Publication | 08/10/2022 | Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8 |
Status:
CompletedInvestigator:
Feinberg, PhilipMentor:
Schafer, DorothyGrant Term:
2 yearsAward Type:
Predoctoral FellowshipsGrant Amount:
$70,000.00Institution Website:
http://www.umassmed.eduGrant ID:
11779