Genome-wide repeat expansions in autism spectrum disorder
This project will use a novel technique to look more closely at regions of the genome currently difficult to sequence called short-tandem repeats (STRs). These STRs have been seen in other neurological disorders and the expansion of these repeats have been associated with greater clinical severity. By improving the identification and quantification of the number of repeats, investigators expect to find additional functional and pathogenic genetic causes for autism.
Grant Term:1 year