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Investigating the effects of disrupting Autism-associated gene SCN2A using human iPS-derived neurons
2019 Postdoctoral Fellowships
University Health Network
Toronto, Ontario
Canada
Toronto, Ontario
Canada
This study will examine the impact of SCN2A genetic variation on synaptic function in human induced pluripotent stem cell neurons. It has the potential to identify targets for testing and developing new ASD therapies.
- Keywords:
- Developmental Neuroscience
- Microscopy
- Electrophysiology - Cellular
- Cellular Biology
- Biochemistry
- Cell Culture
- Neuroscience
- Biology
- Etiology/ Risk Factors
- Treatment/ Prevention
- Children (3-12 Years)
- Adolescents/ Young Adults (13-25 Years)
- Adults (>25 Years)
- Autism Spectrum Disorder
- Other Identifiable Genetic Disorder
- Mice
- Cultured Neurons
- Undifferentiated Cells
- Cell Lines
- Stem Cells
Status:
CompletedInvestigator:
Rosa, ElyseMentor:
Singh, KarunGrant Term:
1 yearAward Type:
Postdoctoral FellowshipsGrant Amount:
$127,600.00Institution Website:
https://www.uhn.ca/Grant ID:
11890